Tsamis, 49, was drafted in the 33rd round by the Toronto Blue Jays after his junior season at Stetson but elected to stay for his senior season. He went 11-3 with a 2.48 ERA in 1989 and the Minnesota Twins were impressed enough to draft him in the 15th round. On April 26, 1993, Tsamis made his major league debut versus the Milwaukee Brewers. He pitched in 41 games for the Twins that season compiling a record of 1-2 with one save.
Following his nine-year professional playing career where he registered a 57-31 minor league record, Tsamis became the pitching coach of the Waterbury (Conn.) Spirit in the Northeast League and was promoted to the managerial role in 1999.
He spent two years there before moving to New Jersey in 2001 where he went 107-72 in the regular season and defeated Winnipeg in the league championship series both years. In 2004, his club rallied past Schaumburg in five games to win the Northern League Championship.
|2001||New Jersey||Northern||—||Independent||45-45||3rd/6||League Champions|
|2002||New Jersey||Northern||—||Independent||62-27||1st/8||League Champions|
|2003||St. Paul||Northern||—||Independent||52-38||3rd/10||Lost Semifinals|
|2004||St. Paul||Northern||—||Independent||61-34||1st/10||League Champions|
|2005||St. Paul||Northern||—||Independent||55-40||2nd/12||Lost Semifinals|
|2006||St. Paul||American Association||—||Independent||52-42||4th/10||Lost Finals|
|2007||St. Paul||American Association||—||Independent||57-39||2nd/10||Lost Finals|
|2008||St. Paul||American Association||—||Independent||42-54||9th/10|
|2009||St. Paul||American Association||—||Independent||49-47||T-4th/10|
|2010||St. Paul||American Association||—||Independent||45-51||7th/10|
|2011||St. Paul||American Association||—||Independent||56-44||3rd/14||Lost Finals|
|2012||St. Paul||American Association||—||Independent||52-48||6th/13|
|2013||St. Paul||American Association||—||Independent||47-53||9th/13|
|2014||St. Paul||American Association||—||Independent||48-52||T-6th/12|
|2015||St. Paul||American Association||—||Independent||74-26||2nd/13||Lost Semifinals|
|2016||St. Paul||American Association||—||Independent||61-39||T-1st/12||Lost Semifinals|
|2017||St. Paul||American Association||—||Independent||48-52||7th/12|
|2018||St. Paul||American Association||—||Independent||59-41||T-4th/12||Lost Finals|